antigen-selected hypermutation

См. также в других словарях:

• Somatic hypermutation — (or SHM) is a mechanism inside cells that is part of the way the immune system adapts to the new foreign elements which confront it (for example, microbes). SHM diversifies the receptors that the immune system uses to recognize foreign elements… …   Wikipedia

• Cytotoxic T cell — Antigen presentation stimulates T cells to become either cytotoxic CD8+ cells or helper CD4+ cells. A cytotoxic T cell (also known as TC, Cytotoxic T Lymphocyte, CTL, T Killer cell, cytolytic T cell, CD8+ T cells or killer T cell) belongs to a… …   Wikipedia

• Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

• Adaptive immune system — The adaptive immune system is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogenic challenges. Thought to have arisen in the first jawed vertebrates, the adaptive or specific immune system is activated …   Wikipedia

• Nicholas Chiorazzi — Nationality American Education Georgetown University School of Medicine Occupation Physician, Scientist Employer The Feinstein Institute for Medical R …   Wikipedia

• Major histocompatibility complex — The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates that encodes MHC molecules. MHC molecules play an important role in the immune system and autoimmunity. Proteins are continually… …   Wikipedia

• Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

• Immunoglobulin class switching — Mechanism of class switch recombination that allows isotype switching in activated B cells Immunoglobulin class switching (or isotype switching or isotypic commutation or class switch recombination(CSR)) is a biological mechanism that changes a B …   Wikipedia

• Polyclonal antibodies — This article deals exclusively with the production of antibodies in vivo. For its medical and biological applications, see Antiserum. Polyclonal antibodies (or antisera) are antibodies that are obtained from different B cell resources. They are a …   Wikipedia

• MSH6 — MutS homolog 6 (E. coli) PDB rendering based on 2gfu …   Wikipedia

• Central tolerance — is the mechanism by which newly developing T cells and B cells are rendered non reactive to self[1]. The concept of central tolerance was proposed in 1959 by Joshua Lederberg[2], as part of his general theory of immunity and tolerance, and is… …   Wikipedia